ADHD medication: a complete UK guide
Page summary
ADHD medication in the UK means stimulant or non-stimulant medicines, started and monitored by an ADHD specialist. The dose is raised in small steps, with regular health checks along the way. Once your dose is settled, a GP may take over prescribing under a shared care agreement. Your prescriber also takes into account other conditions, like autism or anxiety, and medicines you already take. AuDHD Psychiatry prescribes ADHD medication online, after an assessment or a review of an existing diagnosis.

Reviewed by Dr Darren O’Reilly.
Review and publication details
Clinically reviewed by Dr Darren O’Reilly, DPsych, Chartered Psychologist (CPsychol), HCPC registered practitioner psychologist, registration number PYL041661 (check the HCPC register).
AuDHD Psychiatry is the trading name of ADHDdegree Ltd, a company registered in Scotland, company number SC822923. Registered office: 3f1 Third Floor, Hill Street, Edinburgh, EH2 3JP. Registered with the ICO, number ZB823033.
Deciding about ADHD medication can bring up real questions. You might wonder what taking a daily medicine feels like, what people will think, or whether it’ll change who you are. Wanting a clear map before you see a prescriber makes sense. Taking medication is your choice, never a requirement.
- Two groups: stimulants (methylphenidate, lisdexamfetamine and dexamfetamine) and non-stimulants (atomoxetine and guanfacine) [1].
- Who prescribes: an ADHD specialist starts ADHD medicines and monitors them [2].
- Controlled drugs: methylphenidate, lisdexamfetamine and dexamfetamine are each a controlled drug under UK law [3] [4].
- Your GP: a GP can take over prescribing, but only under a shared care agreement [2].
What is ADHD medication?
ADHD medication means prescription medicines that help you manage ADHD symptoms [2]. They can help with symptoms such as trouble concentrating or sitting still [2]. They don’t take ADHD away, though, and they’re one of several ADHD treatment options rather than the whole picture.
NICE guidance sets care standards for the NHS in England. For adults, it offers medication when ADHD still causes a significant problem in at least one area of life [1]. That offer comes after changes to your surroundings, at home or at work, have been made and reviewed [1].
Medication is an option to talk through with a prescriber, not a step you have to take. Not everyone with ADHD needs or wants to take medicine [2]. Some people try more than one medicine before they find one that works for them [2].
Which medicines are used for ADHD in the UK?
NICE guidance names five medicines for ADHD [1]. They fall into two groups, and the table shows where NICE guidance places each one.
| Medicine | Type | Where NICE guidance places it [1] |
| methylphenidate | Stimulant | First choice for children aged 5 and over, and for adults alongside lisdexamfetamine |
| lisdexamfetamine | Stimulant | First choice for adults, alongside methylphenidate; for children if methylphenidate hasn’t helped enough after a 6-week trial at an adequate dose |
| dexamfetamine | Stimulant | Considered when lisdexamfetamine works but its longer effect can’t be tolerated |
| atomoxetine | Non-stimulant | Used when stimulants don’t suit, as the next section explains |
| guanfacine | Non-stimulant | Used for children and young people when stimulants don’t suit |
Any of these medicines can cause side effects [1]. We do not recommend specific medication until after a full clinical assessment. Brand names, and how long each medicine lasts, are set out in ADHD medicines compared.
Stimulant ADHD medication
Stimulant medicines come in slow-release forms, taken once a day, and in standard forms [1]. Guidance favours once-daily forms because they’re convenient, avoid a dose at school or work and are harder to misuse [1]. Your prescriber talks through which form fits your day. Standard forms may suit when the dose needs more flexibility, or while it’s still being found [1]. How well a stimulant works, how long it lasts and its ADHD medication side effects vary from person to person [1]. What suits a friend is no guide to what will suit you.
Your heart rate and blood pressure are checked before and after each dose change, and every 6 months [1]. When you collect methylphenidate, you may need to prove who you are, and you must collect it within 28 days [3]. Our guides cover the best time of day to take ADHD medication and taking ADHD medication daily or only when needed.
Non-stimulant ADHD medication
Non-stimulant ADHD medication is an option when stimulants don’t suit you [1]. Adults are offered atomoxetine if they can’t tolerate lisdexamfetamine or methylphenidate, or neither helped after separate 6-week trials [1]. Children aged 5 and over and young people can be offered atomoxetine or guanfacine on the same basis [1]. Guanfacine is licensed for ages 6 to 17, and adults get it only on advice from a highly specialised service [5] [1].
In trials, suicidal thoughts and behaviour with atomoxetine were uncommon, but more frequent in under-18s than with a dummy pill [6]. So your mood is watched closely while you take it [6]. Tell your prescriber straight away about any low mood or dark thoughts. If stimulants and a non-stimulant haven’t helped, guidance suggests a second opinion or a more specialised service [1]. Our guide explains when to switch ADHD medication.
How is ADHD medication prescribed in the UK?
The route to ADHD medication runs through an ADHD specialist [2]. Before you start, a full review confirms the diagnosis and checks your heart rate, blood pressure, height and weight [1]. The aim is a safe start. Your prescriber then raises the dose in small steps, called titration, until benefits and side effects are best balanced [1]. NICE says to consider slower titration, with more checks, if you also have autism, anxiety or another mental health condition [1]. Our guides cover starting ADHD medication and the signs your dose may need changing.
Before AuDHD Psychiatry prescribes, we ask for your GP summary and blood pressure readings. Your first medication appointment lasts 45 to 60 minutes, and if medication is right for you, your first prescription is issued then. Most people then have 3 to 4 follow-ups, spaced 3 to 4 weeks apart. Our prescribing team includes a consultant psychiatrist, nurse prescribers and a senior clinical pharmacist.
Our medication pathway may suit you if:
- you’ve been diagnosed with ADHD, by us or elsewhere, and want to talk about medication.
- you can complete the safety checks before prescribing.
- you want dose changes made step by step, with regular reviews.
It might not be right today if:
- you need urgent help now. Call NHS 111 and choose the mental health option, or in Northern Ireland call Lifeline free on 0808 808 8000, any time. In an emergency, call 999 or go to A&E [7].
- you mainly want a quick prescription without monitoring.
- you already have a prescriber managing your ADHD medication.
Without a diagnosis, you’d start with an adult ADHD assessment. With one from elsewhere, you can transfer your care to us, and our adult medication pathway shows each step.
Where to go from here
A private online screening with results at the end. It is not a diagnosis.
free ADHD testA free call with our team to ask questions and check which assessment fits.
Book a free 15-minute callWhat is a shared care agreement?
A shared care agreement lets your GP take over prescribing from the specialist [2]. Under the agreement, the specialist and your GP share responsibility and agree who does what. Once your dose is stable, guidance says prescribing and monitoring should move to shared care with your GP practice [1].
Shared care is always your GP’s decision, so it can’t be guaranteed. If your GP doesn’t accept shared care, we carry on prescribing for you privately. If your GP does take over, the NHS prescription rules where you live apply.
Either way, your treatment keeps being checked. ADHD medication should be reviewed at least once a year, including whether to carry on [1]. We review adults’ medication every 6 months. Our guide explains how to pause or stop ADHD medication safely, with your prescriber.
ADHD medication when you’re also autistic
Autistic people with ADHD get the same medication choices as anyone with ADHD [1]. Your prescriber may move through dose changes more slowly, with more frequent checks [1]. So the titration stage can take longer, with more conversations along the way.
It helps to tell your prescriber about sensory sensitivities, routines you rely on and any change in appetite or sleep. Details like these help your prescriber judge how each dose is going. No medicine treats autism itself, so we’ve a separate guide to autism treatment and support. If you haven’t been diagnosed with either condition, you can be assessed for ADHD and autism together at AuDHD Psychiatry.
Can you take ADHD medication with sertraline or other medicines?
Your prescriber checks first whether ADHD medication can be taken with sertraline or another antidepressant [8]. Sertraline is an antidepressant, an SSRI (selective serotonin reuptake inhibitor), used for depression, OCD, panic disorder, PTSD and social anxiety [9]. It isn’t one of the five ADHD medicines above [1]. Anxiety doesn’t narrow your ADHD options, as guidance offers the same choices to people with an anxiety disorder [1].
A few combinations need care. With methylphenidate, tell your prescriber about any medicine for depression or another mental health condition [8]. It must not be taken with MAOI antidepressants, or within 14 days of stopping them, because blood pressure can suddenly rise [8]. Other pairings need care too. Serotonin syndrome, a rare but serious reaction, has been reported when amfetamine medicines such as lisdexamfetamine are taken with SSRIs [10]. Some SSRIs, such as fluoxetine and paroxetine, raise atomoxetine levels, so a lower dose may be needed [6].
Before your medication appointment, list every medicine, supplement and remedy you take. Never stop an antidepressant on your own to start ADHD medication.
What’s different for children?
For children aged 5 and over, methylphenidate is the usual starting point in NICE guidance [1]. During treatment, a child’s height is measured every 6 months and plotted on a growth chart, along with their weight [1]. Our child pathway is for children aged 6 to 17 with an ADHD diagnosis from us or a partner clinic. Children and teenagers may need to try more than one medicine before one suits them [11]. So an early change of medicine is part of the process, not a sign that something has gone wrong. Our page on ADHD medication for children covers the child pathway, its reviews and its fees in full.
What appointments does ADHD medication involve?
ADHD medication involves a first appointment, follow-ups, repeat prescriptions and regular reviews. In order, you can expect:
- an initial medication appointment with a prescriber, after your assessment or a review of your existing diagnosis.
- follow-up appointments during titration, to check how you’re responding, look at side effects and adjust the dose.
- repeat prescriptions once your dose is stable and unchanged.
- medication reviews, every 6 months for adults.
The medicine itself is paid for at the pharmacy, and the amount depends on the brand, dose and pharmacy. If your GP takes over under shared care, you pay us only for your reviews. Each appointment has its own fee, set out on our page about what medication costs. If your pharmacy can’t supply your medicine, our guide explains what to do in an ADHD medication shortage.
Questions people ask
What medication is used for ADHD in adults?
Lisdexamfetamine or methylphenidate is where NICE guidance starts for adults with ADHD [1]. Both are stimulants. Where neither suits you, atomoxetine is the non-stimulant that adults are usually offered next. Your prescriber talks the options through with you and makes the choice after a full assessment, never before it.
Is ADHD medication a controlled drug?
Yes for the three stimulants: methylphenidate, lisdexamfetamine and dexamfetamine are Class B, Schedule 2 controlled drugs [4]. So the pharmacy may check your identity when you collect your medicine. If the label worries you, our guide looks at whether ADHD medication is like taking drugs.
Can you take sertraline for ADHD?
No, sertraline is an antidepressant, and it isn’t a treatment for ADHD symptoms [9] [1]. Anxiety and depression can sit alongside ADHD, and each can be treated in its own right. If you already take sertraline, your prescriber checks how it works with any ADHD medicine before prescribing. Bring a full list of your medicines to that appointment.
Can my GP prescribe ADHD medication?
Not at first, because the specialist writes your early prescriptions, including the very first one, while your dose is being found. If your GP won’t agree to shared care, we can keep prescribing privately, with the same regular reviews.
Do I need a diagnosis to get ADHD medication?
Yes, a full review before you start confirms the diagnosis and that treatment is needed [1]. With AuDHD Psychiatry, medication follows an ADHD assessment with us, or a transfer of care if you were diagnosed elsewhere. For a transfer, we review your assessment and diagnosis, then start treatment if you’re eligible. If you transfer, a clinician reviews your diagnosis and records before any prescribing.
What are the main ADHD medication names?
NICE guidance names five: methylphenidate, lisdexamfetamine, dexamfetamine, atomoxetine and guanfacine [1]. Each is sold under one or more brand names, which differ from the medicine’s own name. Some come in slow-release and standard forms, which last for different lengths of time [1]. Your prescriber explains which one you’d take, and why.
In short
ADHD medicines come in two groups, stimulants and non-stimulants, and an ADHD specialist starts them. Your dose then rises step by step, with health checks at each stage. Once things are steady, your GP may take over under shared care. Other conditions and other medicines are always part of the picture. If you’d like to ask AuDHD Psychiatry a question first, a free 15-minute call is an information call, not an assessment.
Sources
- National Institute for Health and Care Excellence (NICE), guideline NG87, Attention deficit hyperactivity disorder: diagnosis and management, published 14 March 2018, last updated 13 September 2019, https://www.nice.org.uk/guidance/ng87 (read 01/10/2026)
- NHS, ADHD in adults, page last reviewed 19 March 2025, https://www.nhs.uk/conditions/adhd-adults/ (read 01/10/2026)
- NHS, About methylphenidate for adults, page last reviewed 25 March 2025, https://www.nhs.uk/medicines/methylphenidate-adults/about-methylphenidate-for-adults/ (read 01/10/2026)
- Home Office, List of most commonly encountered drugs currently controlled under the misuse of drugs legislation, GOV.UK, updated 1 April 2025, https://www.gov.uk/government/publications/controlled-drugs-list–2/list-of-most-commonly-encountered-drugs-currently-controlled-under-the-misuse-of-drugs-legislation (read 01/10/2026)
- Guanfacine (Intuniv 1 mg prolonged-release tablets), summary of product characteristics, electronic medicines compendium, https://www.medicines.org.uk/emc/product/5099/smpc (read 01/10/2026)
- Atomoxetine (Atomaid 40 mg capsules), summary of product characteristics, electronic medicines compendium, https://www.medicines.org.uk/emc/product/12649/smpc (read 01/10/2026)
- nidirect, Mental health emergency: if you’re in crisis or despair, https://www.nidirect.gov.uk/articles/mental-health-emergency-if-youre-crisis-or-despair (read 29/09/2026)
- NHS, Taking methylphenidate for adults with other medicines and herbal supplements, https://www.nhs.uk/medicines/methylphenidate-adults/taking-methylphenidate-for-adults-with-other-medicines-and-herbal-supplements/ (read 01/10/2026)
- NHS, Sertraline, page last reviewed 8 September 2025, https://www.nhs.uk/medicines/sertraline/ (read 01/10/2026)
- Lisdexamfetamine (Elvanse 20 mg capsules), summary of product characteristics, electronic medicines compendium, https://www.medicines.org.uk/emc/product/14091/smpc (read 01/10/2026)
- NHS, ADHD in children and young people, page last reviewed 19 March 2025, https://www.nhs.uk/conditions/adhd-children-teenagers/ (read 01/10/2026)
About AuDHD Psychiatry
AuDHD Psychiatry is the trading name of ADHDdegree Ltd, a company registered in Scotland. The company number is SC822923. Our registered office is 3f1 Third Floor, Hill Street, Edinburgh, EH2 3JP.
Registered with the ICO, number ZB823033.
Last updated: 13 October 2026
Darren is a Chartered Psychologist and specialist in ADHD and autism, with over 11 years of experience working in mental health and neurodevelopmental services. He holds a Doctorate in Counselling Psychology and has presented research at the British Psychological Society Annual Conference.
Read Darren’s full profileThis article is for general information and does not replace a clinical assessment. If you are struggling with your mental health right now, please contact your GP or NHS 111.